Target Name: DNA ligase
NCBI ID: P11276
Review Report on DNA ligase Target / Biomarker Content of Review Report on DNA ligase Target / Biomarker
DNA ligase
Other Name(s): None

DNA Ligase: A Potential Drug Target and Biomarker

DNA ligase, also known as nonspecified subtype, is a protein that plays a crucial role in the process of DNA repair. DNA ligase is responsible for joining two ends of a broken DNA molecule back together to form a continuous strand. This protein is essential for maintaining the integrity of DNA, which is critical for the proper functioning of all living organisms.

Research has shown that DNA ligase is a potential drug target and may be used as a biomarker for certain diseases. One of the main reasons for this is the fact that DNA ligase is involved in many important cellular processes, including DNA replication, transcription, and repair. As a result, any drug that can inhibit the activity of DNA ligase could potentially have a wide range of therapeutic applications.

DNA ligase is also an important biomarker for certain diseases, such as cancer. In cancer cells, DNA ligase is often overexpressed, which allows the cells to continue to divide and proliferate uncontrollably. By inhibiting the activity of DNA ligase, researchers may be able to develop new treatments for cancer.

Another potential application of DNA ligase as a drug target is the treatment of genetic disorders. Many genetic disorders are caused by mutations in DNA that can disrupt normal cellular processes. In these cases, DNA ligase may be used to repair the damaged DNA and restore normal cellular function.

In addition to its potential therapeutic applications, DNA ligase is also an important protein that is involved in the regulation of cellular processes. This is because DNA ligase is a key component of the immune system, which is responsible for protecting the body against foreign invaders such as viruses and bacteria. By regulating the activity of DNA ligase, the immune system can ensure that it responds effectively to these threats.

Overall, DNA ligase is a protein that plays a crucial role in the process of DNA repair. It is also a potential drug target and biomarker for a wide range of diseases. Further research is needed to fully understand the role of DNA ligase in cellular processes and to develop new treatments based on this protein.

Protein Name: DNA Ligase (nonspecified Subtype)

The "DNA ligase Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DNA ligase comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DNA Methyltransferase (DNMT) | DNA Polymerase alpha | DNA polymerase delta | DNA Polymerase epsilon | DNA Polymerase gamma | DNA Polymerase zeta Complex | DNA primase | DNA topoisomerase | DNA Topoisomerase II | DNA-Dependent Protein Kinase (DNA-PK) | DNA-Directed DNA Polymerase Complex | DNA-Directed RNA Polymerase | DNA-Directed RNA Polymerase I | DNA-Directed RNA Polymerase II | DNA-directed RNA polymerase II, core complex | DNA-directed RNA polymerase III | DNA2 | DNAAF1 | DNAAF10 | DNAAF11 | DNAAF2 | DNAAF3 | DNAAF4 | DNAAF4-CCPG1 | DNAAF5 | DNAAF6 | DNAAF8 | DNAAF9 | DNAH1 | DNAH10 | DNAH11 | DNAH12 | DNAH14 | DNAH17 | DNAH17-AS1 | DNAH2 | DNAH3 | DNAH5 | DNAH6 | DNAH7 | DNAH8 | DNAH8-AS1 | DNAH9 | DNAI1 | DNAI2 | DNAI3 | DNAI4 | DNAI7 | DNAJA1 | DNAJA1P3 | DNAJA1P4 | DNAJA1P5 | DNAJA2 | DNAJA3 | DNAJA4 | DNAJB1 | DNAJB11 | DNAJB12 | DNAJB13 | DNAJB14 | DNAJB2 | DNAJB3 | DNAJB4 | DNAJB5 | DNAJB6 | DNAJB6P1 | DNAJB7 | DNAJB8 | DNAJB8-AS1 | DNAJB9 | DNAJC1 | DNAJC10 | DNAJC11 | DNAJC12 | DNAJC13 | DNAJC14 | DNAJC15 | DNAJC16 | DNAJC17 | DNAJC17P1 | DNAJC18 | DNAJC19 | DNAJC2 | DNAJC21 | DNAJC22 | DNAJC24 | DNAJC25 | DNAJC25-GNG10 | DNAJC27 | DNAJC27-AS1 | DNAJC28 | DNAJC3 | DNAJC3-DT | DNAJC30 | DNAJC4 | DNAJC5 | DNAJC5B | DNAJC5G | DNAJC6 | DNAJC7